Desiderio, an employee of the city under a bizarre reality attack from Doctor Hoffman's mysterious machines, has fallen in love with Albertina, the Doctor's daughter. But Albertina, a beautiful woman made of glass, seems only to appear to him in his dreams.
Meeting on his adventures a host of cannibals, centaurs and acrobats, Desiderio must battle against unreality and the warping of time and space to be with her, as the Doctor reduces Desiderio's city to a chaotic state of emergency - one ridden with madness, crime and sexual excess.
A satirical tale of magic and sex, The Infernal Desire Machines of Doctor Hoffman is a dazzling quest for truth, love and identity.